Using a very unscientific Google Trends query I found the following top 10 US cities that google:

1. Chicago, IL, USA
2. Washington, DC, USA
3. Austin, TX, USA
4. Miami, FL, USA
5. Philadelphia, PA, USA
6. Rochester, NY, USA
7. Raleigh, NC, USA
8. Cincinnati, OH, USA
9. Orlando, FL, USA
10. Dallas, TX, USA

Over all regions:

1. Brisbane, Australia
2. Chicago, IL, USA
3. Philadelphia, PA, USA
4. Houston, TX, USA
5. Dallas, TX, USA
6. San Diego, CA, USA
7. New York, NY, USA
8. Toronto, Canada
9. Sydney, Australia
10. Atlanta, GA, USA

Here is the Google Trends query that was used.

http://www.google.com/trends?q=a+%7C%7C+the+%7C%7C+to+%7C%7C+in+%7C%7C+of+%7C%7C+and+%7C%7C+for+%7C%7C+by+%7C%7C+home+%7C%7C+all+%7C%7C+this+%7C%7C+is+%7C%7C+about+%7C%7C+site+%7C%7C+with+%7C%7C+at+%7C%7C+more+%7C%7C+your+%7C%7C+us+%7C%7C+you+%7C%7C+contact+%7C%7C+web+%7C%7C+are+%7C%7C+from+%7C%7C+information+%7C%7C+it%2C+google%2C+yahoo%2C+ebay%2C+news&ctab=0&geo=US&date=all

I used the 30 most popular words, separated with || (OR does not work) for the search. (http://blogoscoped.com/archive/2006-04-21-n53.html) I also added a few search terms, Google, Yahoo, eBay, and news just to show the search volume.

Interesting! I didn't even know you could use || in Google Trends.

(BTW, just one vertical bar seems to work too.)